The Colonels wrapped up a weekend trip through Illinois with a short bench after another injury forced another starter out of the line-up.
Junior Russhard Cruickshank wasn't able to play on Saturday against SIU-Edwardsville because of concussion-like symptoms.
He is just the latest in a long list of EKU players to miss time so far this season.
"It's part of the game," EKU coach AW Hamilton said of the injuries. "You can't make excuses."
The short-handed Colonels (12-13, 9-3) had their six-game winning streak snapped by the Cougars. EKU was 7-of-37 from three-point range in an 83-75 loss on the road.
The Colonels used just eight players against SIUE -- four of which were on the court for more than 30 minutes.
"We had a lot of adversity going into the SIUE game," Hamilton said. "But, we just didn't play very well. We didn't shoot the ball very well. We missed way too many free throws. It's a game we've got to learn from and we've got to respond."
The Colonels will look to bounce back when they renew an old in-state rivalry today on the road.
EKU is set to take Morehead State (12-13, 6-6 OVC) at 7 p.m. in Johnson Arena.
The Eagles have beaten the Colonels seven of the past eight times the teams have meet, including three-straight.
"It's a big game. We are excited," Hamilton said.
The loss dropped the Colonels into a tie with Belmont (18-7, 9-3) for third place in the OVC. Murray State (11-1) remains in first, while Austin Peay is in second.
With six games left in the regular season, EKU hasn't yet locked up a spot in the OVC tournament, but is closing in on that goal.
Freshman Michael Moreno finished with a double-double of 18 points and 11 rebounds at SIUE.
Moreno was voted the OVC Freshman of the Week on Monday. He averaged 17.5 points and 9.0 rebounds-per-game for the Colonels last week. He shot 69 percent from the field, 56 percent from three-point range and 80 percent from the stripe over the week.
"Michael is getting better every game we play," Hamilton said of Moreno. "He is getting more comfortable on the offense end. He is getting more comfortable shooting threes. He's scary how good he can be."
EKU forced 26 turnovers on Saturday against the Cougars. The Colonels now rank fifth nationally in turnovers forced-per-game (19), sixth nationally in steals-per-game (9.7) and eighth nationally in turnover margin (+5).
Jomaru Brown matched his season high with six assists at SIUE on Saturday.
Ty Taylor (961) and Brown (908) are both within striking distance of reaching 1,000 career points this season.
Morehead State (12-13, 6-6 OVC) also split on the road last weekend, defeating SIUE on Thursday before falling at Eastern Illinois on Saturday.
Jordan Walker paces the Eagles at 13.4 points-per-game.
This is the 193rd all-time meeting between EKU and Morehead State. EKU leads the series, 109-83.
EKU's last win in Morehead came all the way back on January 31, 2015.
EKU women ready to hit road again
The EKU women's basketball snapped a five-game losing streak with a win Saturday over SIU-Edwardsville.
Now, the Colonels (9-14, 3-9 OVC) will look to win back-to-back conference games for the first time this season.
EKU hits the road today to take on long-time rival Morehead State (9-15, 5-7 OVC).
Game time is set for 5 p.m.
Teri Goodlett led the way for the Colonels against SIUE on Saturday, posting a game-high 20 points and seven assists in the win.
Goodlett ranks second in conference play with 4.6 assists per game
I'Liyah Green was named Ohio Valley Conference Newcomer of the Week for the third time this year on Tuesday. The junior averaged 10.5 points per game and six rebounds on 53 percent shooting.
The Colonels rank third in the OVC in field goal percentage defense.
Morehead State fell to Eastern Illinois, 67-62, in overtime on Saturday.
Ariel Kirkwood led the way for the Eagles posting a team-best 15 points and nine rebounds.
The Eagles held Eastern Illinois scoreless in the second quarter on Saturday.
Morehead State ranks fifth in the country in blocks per game.
Jazzmyn Elston ranks 12th in conference play in scoring.