The Indians (8-3) came up just short in a highly anticipated match-up with Bryan Station three weeks ago in Richmond.
And ever since, they've been eager for another opportunity to take on the Defenders (10-1).
"We were right there with them and could have beaten them," Madison Central senior Jeffrey Kinley said of the 21-13 loss to Station on Oct. 22. "Now, we are looking for that revenge on the road."
Central and Station are set to meet again today in the second round of the KHSAA Class 6A Playoffs in Lexington.
The winner claims a district title and moves forward in the postseason.
The loser's season will come to an end.
"Our players are excited. They know the importance of the game," Madison Central coach Mike Holcomb said. "It's been high-energy at practice (all week). We are looking forward to it."
Kick-off is set for 7 p.m. at Bryan Station.
The Defenders have won five-straight against the Indians.
Their most recent victory gave them the regular-season district title and home-field advantage for a possible postseason meeting with the Indians.
Both teams rolled to wins last week in the first round of the playoffs.
Central topped Oldham County, 42-9, while Station blasted Clark County, 45-0.
"We got the rematch we wanted," Kinley said.
The Indians put together one of their best all-around performances of the season against the Colonels. Central forced five turnovers (including a fumble return for a TD by Kinley) and had 422 yards of total offense.
Sophomore Brady Hensley had 168 yards rushing and three TDs, while quarterback Hagan Harrison finished with a career-best 156 yards passing.
The Indians had gained only 116 total yards through the air in their previous four games, but got a 61-yard TD catch by Jayden West and 23-yard TD catch by Travis Grant.
"We were able to do some things. We were able to throw the ball around a little bit and get some big plays," Holcomb said. "Our running game helped and our offensive line played great again."
Station also put together another great performance last week.
The Defenders limited Clark County to just 70 yards of offense and only six first downs on their way to their fourth shutout of the season.
Station has allowed 127 points -- the second-fewest of any Class 6A team in the state.
Jeremiah Mundy-Lloyd had two rushing touchdowns against the Cardinals, while Joseph Bond had 125 yards rushing an a score. Quarterback Trenton Cutwright was 8-of-12 for 96 yards with one touchdown.
"They are well-coached. They do what they do well. They do what they are supposed to do," Holcomb said of Station, which has won 10-straight games. "They have a lot of quickness."
The speedy Defenders had 379 yards of offense in the first meeting with Central -- 203 yards of which came on three big pass plays.
Javoen Hurt had a 58-yard TD catch in the first quarter and Jmarious Lindsey caught 57-yard TD in the second quarter. Hurt sealed the victory with a 78-yard score after a reception with 1:10 left in regulation.
"Every play is important. You can't have breakdowns on either side of the ball," Holcomb said.
One play made a big difference the last time Station and Central met in the playoffs.
A bad snap led to a missed extra-point attempt by Central with 1:50 left in regulation of a first-round showdown last November in Lexington.
The Defenders were able to hold on for a 14-13 win.
Central's last victory over Station was on Oct. 27, 2017.
"If you get the job done, you get to move on," Holcomb said. "That's what is all about."