The Indians got a chance to avenge a loss in last year's 11th Region Tournament when they faced Scott County on Tuesday in Georgetown.
They didn't get off to a good start, though.
Madison Central (6-10) trailed by double-digits in the first quarter and was never really able to recover.
Terrin Hamilton had 33 points and 10 rebounds as the Cardinals (7-8) pulled away for a 74-60 win. Scott County hit 16-of-18 free throws and led by as much as 21 points in the second half.
Kole Browne had 18 points to lead Central. Taishon Chenault had 13 points. Trey Skaggs had eight points and a team-best four rebounds.
Carter Buckner and Jaylen Davis had seven points each, while Luke Coleman and Alex Rogers had two points each.
Central shot 46 percent from the field, including 54 percent in the second half.
The Indians were 3-of-12 from three-point range with Bucker, Browne and Chenault all connecting once from long range.
Central had only nine assists on 23 field goals.
Scott County was 4-of-16 from three-point range and shot 51 percent from the field for the game.
The Cardinals had 14 second-chance points and 18 points off 14 Central turnovers.
The Indians will look to snap a two-game losing streak when they take on Great Crossing on Saturday at home. Tip-off is set for 7:30 p.m.