The short-handed Indians led by as much as nine points, but were able to hold off a late rally by Pikeville on Saturday in Richmond.
The Panthers (5-1) out-scored the Indians 21-10 in the fourth quarter and rallied for a 69-61 win.
Kole Browne had 27 points and four rebounds for Central, which was without two starters - Braeden Ray and Will Hardin. Jaylen Davis had 18 points, hit three three-pointers and pulled down nine rebounds.
The Indians hadn't played in eight days because of COVID-19 related issues.
On Saturday, they trailed 19-17 after the first quarter before taking a 37-32 lead into halftime.
Central shot 56.5 percent in the first half.
The Indians, however, shot 26 percent from the field in the second half.
The Panthers got within three points (51-48) after three quarters, then surged in final period.
Kenyatta Hardge had seven points and seven rebounds. Taishon Chenault had five points and three rebounds, while Trey Skaggs had four points, five assists and three rebounds.
Central is set to return to action Monday at 11th Region rival Frederick Douglass in Lexington.
Berea's Dorsey reaches 1,000 points
Berea Community's Jaylen Dorsey reached a special milestone on Saturday afternoon.
The senior scored 13 points, including his 1,000th point, and had 16 rebounds as the Pirates (1-3) were handed a 78-63 loss at home by Frankfort (4-4).
Back on the court for the first time in 11 days, Berea fell behind early. The Panthers led 14-6 after the first quarter and were up 28-20 at halftime.
Jayden Smith had 20 points and 13 rebounds for Berea. Trenton Wilson hit five three-pointers and finished with 19 points.
Quenten Morgan had five points. James Brennan had four points and Isaiah Dorsey added two points.
The Pirates are set to return to action Tuesday at home against Trinity Christian.
Lady Eagles fall at Mercer County
The Madison Southern girls basketball team had its four-game winning streak snapped with a 75-40 loss on Saturday at Mercer County.
The Lady Eagles (6-2) were down 25-2 after the first quarter and went into halftime trailing 42-13.
Samantha Cornelison had 17 points and Lacie Parks had seven points for Southern. Reece Estep had five points. Ashlan Estep had three points, while Macie Daniels and Morgan Flannery had two points each.
The Lady Eagles are set to return to Wednesday at Tates Creek.