The Indians (1-5) once again put together a late comeback.
This time, however, it was too little and too late.
Madison Central scored two second-half touchdowns, but Dixie Heights came up with a interception in the closing minutes and held on for a 38-23 win on Friday in Richmond.
Ashton Hulberg had a touchdown catches on the night he was named Homecoming King, while Adrien Parks and John Landsaw also had TD for the Indians.
Central rallied for a 24-18 win over Lafayette last week on the road.
In the fourth quarter this season, the Indians have out-scored their opponents 50-28.
The Colonels took a 35-9 lead with 5:22 left in the third quarter, but the Indians didn't quit.
Landsaw caught a 25-yard TD pass from Canon Scenters moments later and Hulberg hauled in a 5-yard TD pass in the fourth quarter to cut the lead to 12 points.
Dixie Height's Logan Sansone connected on a 52-yard field goal.
Central got the ball back and got into the red zone before Scenters was intercepted.
The Indians finished with almost 100 more yards of total offense than the Colonels (387 to 292) and both teams had two turnovers.
Dixie Height jumped on top early and never trailed.
It took the Colonels just six plays and just more than two minutes to score on the opening possession. Leon Marshall had a two-yard touchdown run.
Dixie Heights (2-3) had been shutout in three of their four games this season.
The Indians responded with a 22-yard field goal by Patrick Moren.
Marshall scored on an 11-yard run with 1:07 left in the first quarter.
Parks found the end zone from 11 yards out early in the second quarter. The conversion failed leaving the Colonels with a 14-9 lead.
Logan Landers added added two touchdown passes before the half to give Dixie Heights a 28-9 lead at the break.
The quarterback connected with Jeremy Adams on a 26-yard TD pass in the third quarter that pushed the advantage to 26 points.
The game featured a one-hour lightning delay near the end of the first quarter.
Central had 22 first downs (Dixie Heights had 16), but was 3-of-11 on third downs.
Matt Jones had a team-best 148 yards rushing on 18 carries for Central. Parks had 75 yards rushing.
Zach Holbrook caught 6 passes for 55 yards. Landsaw had five catches for 86 yards and Hulberg had two catches for 14 yards.
Scenters was 13-of-27 for 155 yards with two touchdowns and one interception.
Central is off next week and will return to action Oct. 11 at Oldham County.